[CAS NO. 3476-86-6]??SU5205
PRODUCTS SPECIFICATIONS [3476-86-6]
DESCRIPTION [3476-86-6]
Overview
| MDL | MFCD00435356 |
|---|---|
| Molecular Weight | 239.24 |
| Molecular Formula | C15H10FNO |
| SMILES | O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(F)C=C3 |
Summary
SU5205 is an inhibitor of VEGFR2 (FLK-1) , with an IC 50 of 9.6 μM [1] .
IC50 & Target
|
Flk-1 9.6 μM (IC 50 ) |
In Vitro
SU5205 inhibits ligand-induced endothelial mitogenesis for VEGF with an IC 50 of 5.1 μM [1] .
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance
Solid
Shipping
Room temperature in continental US; may vary elsewhere.
Storage
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
Solvent & Solubility
DMSO : 250 mg/mL ( 1044.98 mM ; Need ultrasonic)
Stock Solutions
| Concentration Solvent Mass | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 4.1799 mL | 20.8995 mL | 41.7990 mL |
| 5 mM | 0.8360 mL | 4.1799 mL | 8.3598 mL |
| 10 mM | 0.4180 mL | 2.0900 mL | 4.1799 mL |