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[CAS NO. 38647-11-9]??Triptonide

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PRODUCTS SPECIFICATIONS [38647-11-9]

Catalog
SLK-S9416
Brand
Selleck
CAS
38647-11-9

DESCRIPTION [38647-11-9]

Overview

MDLMFCD00210566
Molecular Weight358.39
Molecular FormulaC20H22O6
SMILESC[C@@]12[C@@]34[C@@]5([C@@](O5)(C[C@]1(C6=C(CC2)C(=O)OC6)[H])[H])C(=O)[C@]7([C@H](C)C)[C@]([C@@]3(O4)[H])(O7)[H]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Triptonide, isolated from the roots of Tripterygium wilfordii, can effectively inhibit canonical signaling by targeting the downstream C-terminal transcription domain of β-catenin or a nuclear component associated with β-catenin. It is also an antineoplastic agent, an anti-inflammatory agent and an immunosuppressive agent.

Targets

Wnt/β-catenin [1]


Synonyms

Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-
Triptolide, 14-deoxy-14-oxo-
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan, triptolide deriv.
(3bS,4aS,5aS,6aS,7aS,7bS,8aS,8bS)-3b,4,4a,7a,7b,8b,9,10-Octahydro-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione
Triptonide
Triptonid
(-)-Triptonide
Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1,6(3H,6aH)-dione, 3b,4,4a,7a,7b,8b,9,10-octahydro-8b-methyl-6a-(1-methylethyl)-, [3bS-(3bα,4aα,5aR*,6aβ,7aβ,7bα,8aR*,8bβ)]-
NSC 165677
PG 492

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