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[CAS NO. 42553-65-1]??Crocin

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PRODUCTS SPECIFICATIONS [42553-65-1]

Catalog
HY-N0697
Brand
MCE
CAS
42553-65-1

DESCRIPTION [42553-65-1]

Overview

MDLMFCD11044877
Molecular Weight976.96
Molecular FormulaC44H64O24
SMILESO[C@@H]([C@H](O)[C@H]1O)[C@H](O[C@H]1OC(/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=O)=O)CO[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO

For research use only. We do not sell to patients.


Summary

Crocin (Crocin I) is a nutraceutical and the main constituent isolated from the stigmas of Crocus sativus with immense pharmacological properties as anti-inflammatory, anticancer, antidepressant and anticonvulsant [1] .


Clinical Trial

NCT Number Sponsor Condition Start Date Phase
NCT05504148 Qilu Hospital of Shandong University
Breast Cancer
March 29, 2021 Not Applicable
NCT04936490 Shiraz University of Medical Sciences
Chorioretinopathy, Central Serous
July 1, 2021 Phase 1
NCT03375814 Mashhad University of Medical Sciences
Osteoarthritis, Knee
July 20, 2016 Phase 3

Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL ( 127.95 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0236 mL 5.1179 mL 10.2358 mL
5 mM 0.2047 mL 1.0236 mL 2.0472 mL
10 mM 0.1024 mL 0.5118 mL 1.0236 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.08 mg/mL (2.13 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.13 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

β-D-Glucopyranose, 6-O-β-D-glucopyranosyl-, 1,1′-[(2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate]
Crocin
8,8′-Diapo-ψ,ψ-carotenedioic acid, bis(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl) ester
α-Crocin
Crocin 1
all-trans-Crocetin di-β-D-gentiobiosyl ester
Crocetin bis(gentiobiosyl) ester
Crocin 4
Crocetin digentiobioside
Crocin A
trans-Crocetin di(β-D-gentiobiosyl) ester
Crocetin di(β-D-gentiobiosyl) ester
Crocetin di-β-gentiobiosyl ester
Crocin I
trans-Crocin-1
Trans-crocin-1
Kiriyasu Oil Yellow GY

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