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[CAS NO. 485-91-6]??Allocryptopine

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PRODUCTS SPECIFICATIONS [485-91-6]

Catalog
HY-N1933
Brand
MCE
CAS
485-91-6

DESCRIPTION [485-91-6]

Overview

MDL-
Molecular Weight369.41
Molecular FormulaC21H23NO5
SMILESO=C1C(C(CCN(C)CC2=C(OC)C(OC)=CC=C2C1)=C3)=CC4=C3OCO4

For research use only. We do not sell to patients.

Summary

Allocryptopine, a derivative of tetrahydropalmatine, is extracted from Macleaya cordata (Thunb.) Pers. Papaveraceae . Allocryptopine has antiarrhythmic effects and potently blocks human ether-a-go-go related gene (hERG) current [1] [2] .


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL ( 135.35 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7070 mL 13.5351 mL 27.0702 mL
5 mM 0.5414 mL 2.7070 mL 5.4140 mL
10 mM 0.2707 mL 1.3535 mL 2.7070 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.77 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

[1,3]Benzodioxolo[5,6-e][2]benzazecin-14(6H)-one, 5,7,8,15-tetrahydro-3,4-dimethoxy-6-methyl-
α-Fagarine
5,7,8,15-Tetrahydro-3,4-dimethoxy-6-methyl[1,3]benzodioxolo[5,6-e][2]benzazecin-14(6H)-one
β-Homochelidonine
α-Allocryptopine
Thalictrimine
Allocryptopine
Thalictrimine (C21 alkaloid)
α-allo-Cryptopine

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