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[CAS NO. 541-22-0]??Decamethonium Bromide

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PRODUCTS SPECIFICATIONS [541-22-0]

Catalog
SLK-S4072
Brand
Selleck
CAS
541-22-0

DESCRIPTION [541-22-0]

Overview

MDL-
Molecular Weight418.29
Molecular FormulaC16H38N2.2Br
SMILESC([N+](C)(C)C)CCCCCCCCC[N+](C)(C)C.[Br-]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.3907 mL11.9534 mL23.9069 mL
5 mM0.4781 mL2.3907 mL4.7814 mL
10 mM0.2391 mL1.1953 mL2.3907 mL
50 mM0.0478 mL0.2391 mL0.4781 mL

Description

Decamethonium Bromide is a nicotinic partial agonist and blocking agent.

Targets

nAChR [1]

In vitro

Decamethonium (Syncurine) is a depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. Decamethonium, which has a short action time, is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor. In the motor endplate, it causes depolarization, preventing further effects to the normal release of acetylcholine from the presynaptic terminal, and therefore preventing the neural stimulus from affecting the muscle. In the process of binding, decamethonium actually activates (depolarizes) the motor endplate, but since the decamethonium itself is not degraded, the membrane remains depolarized and unresponsive to normal acetylcholine release.


Synonyms

1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-hexamethyl-, bromide (1:2)
Ammonium, decamethylenebis[trimethyl-, dibromide
1,10-Decanediaminium, N,N,N,N′,N′,N′-hexamethyl-, dibromide
Ammonium, decamethylenebis[trimethyl- bromide]
C 10 (onium compound)
Decamethonium dibromide
Decamethylenebis[trimethylammonium bromide]
Decamethylene-1,10-bistrimethylammonium dibromide
Syncurine
Decamethonium bromide
Decacuran
C 10

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