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[CAS NO. 54857-86-2]??TOFA (5-(Tetradecyloxy)-2-furoic acid)

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PRODUCTS SPECIFICATIONS [54857-86-2]

Catalog
SLK-S6690
Brand
Selleck
CAS
54857-86-2

DESCRIPTION [54857-86-2]

Overview

MDLMFCD01726059
Molecular Weight324.45
Molecular FormulaC19H32O4
SMILESO(CCCCCCCCCCCCCC)C=1OC(C(O)=O)=CC1

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM3.0821 mL15.4107 mL30.8214 mL
5 mM0.6164 mL3.0821 mL6.1643 mL
10 mM0.3082 mL1.5411 mL3.0821 mL
50 mM---

Description

TOFA (5-(Tetradecyloxy)-2-furoic acid, Tyrphostin 46,Tyrphostin A46,Tyrphostin B40) is an allosteric inhibitor of . Inside the cell, TOFA is converted to TOFyl-CoA (5-tetradecyloxy-2-furoyl-CoA), exerting an allosteric inhibition on ACCA. TOFA blocks fatty acid synthesis and induces cell death in a dose-dependent manner.

Targets

ACCA [1]


Synonyms

2-Furancarboxylic acid, 5-(tetradecyloxy)-
5-(Tetradecyloxy)-2-furancarboxylic acid
RMI 14514
5-(Tetradecyloxy)-2-furoic acid
RMI 14,514
MDL 14514

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