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[CAS NO. 565-73-1]??Sodium oxamate

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PRODUCTS SPECIFICATIONS [565-73-1]

Catalog
SLK-S6871
Brand
Selleck
CAS
565-73-1

DESCRIPTION [565-73-1]

Overview

MDLMFCD00044553
Molecular Weight111.03
Molecular FormulaC2H2NNaO3
SMILESC(C(O)=O)(N)=O.[Na]

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Description

Sodium oxamate (SO, Aminooxoacetic acid, Oxamic acid) is an inhibitor of that specificly inhibits LDH?A. Sodium oxamate (SO) induces G2/M cell cycle arrest via downregulation of the pathway and promotes through enhancement of mitochondrial generation.

Targets

LDHA [1]ROS [2]CDK1 [2]

In vitro

Sodium oxamate, a specific inhibitor of LDH-A, enhances the suppressive effects of PARP inhibitors on ovarian cancer without BRCA mutations, remarkably promoting the inhibitory effects of PARP inhibitors on wild-type BRCA ovarian cancer cells.


Synonyms

Acetic acid, 2-amino-2-oxo-, sodium salt (1:1)
Oxamic acid, sodium salt
Oxamic acid, monosodium salt
Acetic acid, aminooxo-, monosodium salt
Sodium oxamate

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