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[CAS NO. 566203-88-1]??AZD2098

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PRODUCTS SPECIFICATIONS [566203-88-1]

Catalog
SLK-S6555
Brand
Selleck
CAS
566203-88-1

DESCRIPTION [566203-88-1]

Overview

MDLMFCD31382158
Molecular Weight334.18
Molecular FormulaC11H9Cl2N3O3S
SMILESO=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.9924 mL14.9620 mL29.9240 mL
5 mM0.5985 mL2.9924 mL5.9848 mL
10 mM0.2992 mL1.4962 mL2.9924 mL
50 mM0.0598 mL0.2992 mL0.5985 mL

Description

AZD2098 is a potent and bioavailable antagonist with pIC50 of 7.8.

Targets

rat CCR4 [1]mouse CCR4 [1]hCCR4 [1]dog CCR4 [1]
8(pIC50)8(pIC50)7.8(pIC50)7.6(pIC50)

In vitro

AZD2098 demonstrates good selectivity for the CCR4 receptor when screened in-house against a range of other chemokine receptors (CXCR1 and CXCR2, CCR1, CCR2b, CCR5, CCR7, and CCR8; all inactive at 10 μM) and little or no activity when screened against a large panel of receptors and enzymes.


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