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[CAS NO. 6807-83-6]??Trifolirhizin

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PRODUCTS SPECIFICATIONS [6807-83-6]

Catalog
HY-N0616
Brand
MCE
CAS
6807-83-6

DESCRIPTION [6807-83-6]

Overview

MDLMFCD00238700
Molecular Weight446.40
Molecular FormulaC22H22O10
SMILESO[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC=C3C(OC[C@]4([H])[C@@]3([H])OC5=C4C=C(OCO6)C6=C5)=C2

For research use only. We do not sell to patients.

Summary

Trifolirhizin is a pterocarpan flavonoid isolated from the roots of Sophora flavescens . Trifolirhizin possesses potent tyrosinase inhibitory activity with an IC 50 of 506 μM [1] . Trifolirhizin exhibits potential anti-inflammatory and anticancer activities [2] .


IC50 & Target

IC50: 506 μM (tyrosinase) [1]


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)


Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 224.01 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2401 mL 11.2007 mL 22.4014 mL
5 mM 0.4480 mL 2.2401 mL 4.4803 mL
10 mM 0.2240 mL 1.1201 mL 2.2401 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

  • 3.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.60 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

β-D-Glucopyranoside, (6aR,12aR)-6a,12a-dihydro-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl
Trifolirhizin
β-D-Glucopyranoside, 6a,12a-dihydro-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl, (6aR-cis)-
6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran, β-D-glucopyranoside deriv.
(6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3-yl β-D-glucopyranoside
Sophojaponicin B1
(-)-Maackiain-3-O-glucoside
(6aR,11aR)-Trifolirhizin

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