Linalool (i.p. 10-200mg/kg; p.o., 5-100mg/kg) shows significant antinociceptive activity against glutamate induced pain in mice, possible due mechanisms operated by ionotropic glutamate receptors, namely AMPA, NMDA and kainate but not via metabotropic receptors. Linalool (50-150mg/kg, s.c.) shows antinociceptive activity in formalin and hot-plate tests. This effect is mediated by NMDA, opioid dopamine D2, muscarinic M2 receptors and KATP channels. Linalool (50 and 100mg/kg doses) impairs long-term memory acquisition, but not short-term memory acquisition, in the object recognition task in rats.