一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

[CAS NO. 894783-71-2]??BIBF1202

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [894783-71-2]

Catalog
HY-15992
Brand
MCE
CAS
894783-71-2

DESCRIPTION [894783-71-2]

Overview

MDL-
Molecular Weight525.60
Molecular FormulaC30H31N5O4
SMILESO=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)O

For research use only. We do not sell to patients.

Summary

BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC 50 of 62 nM.


IC50 & Target

IC50: 62 nM (VEGFR2) [1]


In Vitro

The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.


Appearance

Solid


Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 45 mg/mL ( 85.62 mM )

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9026 mL 9.5129 mL 19.0259 mL
5 mM 0.3805 mL 1.9026 mL 3.8052 mL
10 mM 0.1903 mL 0.9513 mL 1.9026 mL
* Please refer to the solubility information to select the appropriate solvent.


互助| 抚顺市| 五大连池市| 通州市| 天等县| 兴文县| 崇左市| 武汉市| 萝北县| 瑞丽市| 大英县| 厦门市| 乌审旗| 京山县| 苗栗县| 兖州市| 旬邑县| 含山县| 柏乡县| 光泽县| 牟定县| 安吉县| 牟定县| 鲜城| 台前县| 松桃| 兴国县| 嘉兴市| 高安市| 阜宁县| 包头市| 石家庄市| 闻喜县| 岳西县| 阿城市| 邻水| 富宁县| 上蔡县| 荆州市| 彭水| 莆田市|