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[CAS NO. 93-29-8]??Isoeugenol acetate

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PRODUCTS SPECIFICATIONS [93-29-8]

Catalog
HY-N6805
Brand
MCE
CAS
93-29-8

DESCRIPTION [93-29-8]

Overview

MDLMFCD00026984
Molecular Weight206.24
Molecular FormulaC12H14O3
SMILESCC(OC1=CC=C(C=C1OC)/C=C/C)=O

For research use only. We do not sell to patients.

Summary

Isoeugenol acetate (Acetyl isoeugenol), an essential oil constituent of nutmeg, clove, and cinnamon, shows excellent inhibitory effects against some metabolic enzymes such as acetylcholinesterase (AChE) enzymes ( IC 50 =77 nM; K i =16 nM), α-glycosidase ( IC 50 =19.25 nM; K i =21 nM), and α-amylase ( IC 50 =411.5 nM). Isoeugenol acetate is used medical and cosmetics industries for its antioxidant, anticancer, antimicrobial and anti-inflammatory properties [1] [2] .


IC50 & Target

IC50: 77 nM (AChE), 19.25 nM (α-glycosidase), 411.5 nM (α-amylase) [1]
Ki: 16 nM (AChE), 21 nM (α-glycosidase) [1]


Appearance

Solid



Shipping

Room temperature in continental US; may vary elsewhere.


Storage

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL ( 484.87 mM ; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8487 mL 24.2436 mL 48.4872 mL
5 mM 0.9697 mL 4.8487 mL 9.6974 mL
10 mM 0.4849 mL 2.4244 mL 4.8487 mL
* Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one: 10% DMSO >> 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (12.12 mM); Clear solution

  • 2.

    Add each solvent one by one: 10% DMSO >> 90% corn oil

    Solubility: ≥ 2.5 mg/mL (12.12 mM); Clear solution

* All of the co-solvents are available by MCE.


Synonyms

Phenol, 2-methoxy-4-(1-propen-1-yl)-, 1-acetate
Phenol, 2-methoxy-4-propenyl-, acetate
Isoeugenol, acetate
Phenol, 2-methoxy-4-(1-propenyl)-, acetate
4-Acetoxy-3-methoxy-1-propenylbenzene
Acetylisoeugenol
Isoeugenyl acetate
2-Methoxy-4-propenylphenyl acetate
O-Acetylisoeugenol
NSC 46121

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