一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

[CAS NO. 954126-98-8]??Danirixin (GSK1325756)

Ships within Stock Price Qty Total
$0.00
$0.00
Please click "REQUEST A QUOTE" button if you need other sizes or custom synthesis
request a quote
If there is no stock, or you need other sizes or custom synthesis, please:

PRODUCTS SPECIFICATIONS [954126-98-8]

Catalog
SLK-S6620
Brand
Selleck
CAS
954126-98-8

DESCRIPTION [954126-98-8]

Overview

MDLMFCD27987922
Molecular Weight441.90
Molecular FormulaC19H21ClFN3O4S
SMILESO=C(NC1=CC=C(Cl)C(S([C@H]2CCCNC2)(=O)=O)=C1O)NC3=C(C)C(F)=CC=C3

For research use only.

Storage

3 years,-20°C,powder
1 years,-80°C,in solvent

Shipping

Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

1 mg5 mg10 mg
1 mM2.2630 mL11.3148 mL22.6296 mL
5 mM0.4526 mL2.2630 mL4.5259 mL
10 mM0.2263 mL1.1315 mL2.2630 mL
50 mM0.0453 mL0.2263 mL0.4526 mL

Description

Danirixin (GSK1325756) is a small molecule, non-peptide, high affinity (IC50 for binding?=?12.5 nM), selective, and reversible antagonist.

Targets

CXCR2 [2]CXCL8 [2]
12.5 nM

In vitro

Danirixin has high affinity for CXCR2, with a negative log of the 50% inhibitory concentration (pIC50) of 7.9 for binding to Chinese hamster ovary cell (CHO)-expressed human CXCR2, and 78-fold selectivity over binding to CHO-expressed CXCR1. Danirixin is a competitive antagonist against CXCL8 in Ca2+-mobilization assays, with a K of 6.5 nM and antagonist potency (pA2) of 8.44 and is fully reversible in washout experiments over 180 minutes.


西城区| 潞城市| 兰西县| 堆龙德庆县| 宜阳县| 汕尾市| 迁西县| 吴川市| 肇州县| 洞口县| 屏山县| 香港 | 电白县| 龙门县| 略阳县| 阿鲁科尔沁旗| 高邮市| 徐州市| 济阳县| 苏尼特右旗| 嵊泗县| 开原市| 兴化市| 育儿| 蕉岭县| 苏尼特右旗| 巴里| 长治县| 北宁市| 皋兰县| 宣城市| 康乐县| 尚义县| 江口县| 永年县| 海林市| 舟曲县| 灯塔市| 家居| 崇文区| 阳高县|