Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
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Pyridine?is a?basic?heterocyclic?organic compound?with the?chemical formula?C5H5N. It is structurally related to?benzene, with one?methine group?(=CH?)?replaced by a?nitrogen?atom. It is a highly flammable, weakly?alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
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