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  1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Aminooxy-amido-PEG4-propargyl

Aminooxy-amido-PEG4-propargyl 是一種不可降解 (non-cleavable) 的含 4 個(gè)單元 PEG 的 ADC linker,可用于合成抗體偶聯(lián)活性分子 (ADC)。Aminooxy-amido-PEG4-propargyl 是一種點(diǎn)擊化學(xué)試劑。它含有 Alkyne 基團(tuán),可以和含有 Azide 基團(tuán)的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應(yīng) (CuAAc)。

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Aminooxy-amido-PEG4-propargyl

Aminooxy-amido-PEG4-propargyl Chemical Structure

CAS No. : 2253965-03-4

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50 mg ¥720
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100 mg ¥1136
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250 mg ¥1902
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1 g ¥5498
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  • 生物活性

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生物活性

Aminooxy-amido-PEG4-propargyl is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-amido-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target

Non-cleavable Linker

 

體外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

304.34

Formula

C13H24N2O6

CAS 號(hào)
性狀

粘稠液體

顏色

Colorless to light yellow

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度 & 產(chǎn)品資料
參考文獻(xiàn)
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