3 | 176652-07-6 | Qinghaosu-d3 | NSC 369397-d3 | 青蒿素 d3 | Parasite | Akt | HCV | Ferroptosis | PKB | Protein kinase B | Hepatitis C virus | Inhibitor | inhibitor | inhibit"/>

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  1. PI3K/Akt/mTOR Anti-infection Apoptosis
  2. Parasite Akt HCV Ferroptosis
  3. Artemisinin-d3

Artemisinin-d3 是 Artemisinin 的氘代物。Artemisinin (Qinghaosu) 是一種倍半萜烯內(nèi)酯,從青蒿 (Artemisia annua L.) 植物的地上部分分離的抗瘧疾活性分子。Artemisinin 以劑量依賴性方式降低 pAKT 來(lái)抑制 AKT 信號(hào)通路。Artemisinin 可減少癌細(xì)胞的增殖,遷移,侵襲,腫瘤發(fā)生和轉(zhuǎn)移,同時(shí) Artemisinin 有神經(jīng)保護(hù)作用。

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Artemisinin-d<sub>3</sub>

Artemisinin-d3 Chemical Structure

CAS No. : 176652-07-6

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規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ¥10260
3 - 4 周
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Other Forms of Artemisinin-d3:

查看 Parasite 亞型特異性產(chǎn)品:

查看 Akt 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Artemisinin-d3 is the deuterium labeled Artemisinin. Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].

產(chǎn)品應(yīng)用

1. 該化合物可作為示蹤劑。
2. 該化合物可作為 NMR、GC-MS 或 LC-MS 分析中的內(nèi)標(biāo)品,用于定量分析。

IC50 & Target

Plasmodium

 

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

285.35

Formula

C15H19D3O5

CAS 號(hào)
非標(biāo)記 CAS
中文名稱

青蒿素 d3

運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產(chǎn)品資料
參考文獻(xiàn)
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產(chǎn)品名稱:
Artemisinin-d3
目錄號(hào):
HY-B0094S
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