7 | 919514-01-5 | | 度洛西汀-d7 | Isotope-Labeled Compounds | Serotonin Transporter | 5-HTT | SERT | SLC6A4 | Inhibitor | inhibitor | inhibit"/>

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  1. Others Neuronal Signaling
  2. Isotope-Labeled Compounds Serotonin Transporter
  3. Duloxetine-d7

Duloxetine-d7 是 Duloxetine 的氘代物。Duloxetine ((S)-Duloxetine) 是 5 羥色胺-去甲腎上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制劑,Ki 為 4.6 nM,可作用于廣泛性焦慮癥。

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Duloxetine-d<sub>7</sub>

Duloxetine-d7 Chemical Structure

CAS No. : 919514-01-5

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Other Forms of Duloxetine-d7:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Duloxetine-d7 ((S)-Duloxetine-d7) is the deuterium labeled Duloxetine. Duloxetine is a serotonin-norepinephrine reuptake inhibitor with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD)[1][2].

產(chǎn)品應(yīng)用

1. 該化合物可作為示蹤劑。
2. 該化合物可作為 NMR、GC-MS 或 LC-MS 分析中的內(nèi)標(biāo)品,用于定量分析。

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

304.46

Formula

C18H12D7NOS

CAS 號
非標(biāo)記 CAS
性狀

油狀物

顏色

Colorless to light yellow

中文名稱

度洛西汀-d7

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
純度 & 產(chǎn)品資料

純度: 97.32%

參考文獻
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產(chǎn)品名稱:
Duloxetine-d7
目錄號:
HY-B0161S
需求量:
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