6 | 1217644-84-2 | Isotope-Labeled Compounds | 5-HT Receptor | Endogenous Metabolite | Serotonin Receptor | 5-hydroxytryptamine Receptor | Inhibitor | inhibitor | inhibit"/>

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  1. Others GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds 5-HT Receptor Endogenous Metabolite
  3. Zolmitriptan-d6

Zolmitriptan-d6 是 Zolmitriptan 氘代物。Zolmitriptan (BW-311C90; 311C90) 是一種 5-HT1B/1D 受體部分激動(dòng)劑,對 5-HT1B、5-HT1D、5-HT1F 受體的 Ki 分別為 5.01 nM、0.63 nM 和 63.09 nM。Zolmitriptan可用于偏頭痛的研究

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Zolmitriptan-d<sub>6</sub>

Zolmitriptan-d6 Chemical Structure

CAS No. : 1217644-84-2

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Other Forms of Zolmitriptan-d6:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Zolmitriptan-d6 is deuterium labeled Zolmitriptan. Zolmitriptan (BW-311C90; 311C90) is a 5-HT1B/1D receptor partial agonist with Kis of 5.01 nM, 0.63 nM, and 63.09 nM for 5-HT1B, 5-HT1D, 5-HT1F receptor, respectively. Zolmitriptan can be used for the research of migraine[1][2].

產(chǎn)品應(yīng)用

1. 該化合物可作為示蹤劑。
2. 該化合物可作為 NMR、GC-MS 或 LC-MS 分析中的內(nèi)標(biāo)品,用于定量分析。

IC50 & Target

5-HT1B Receptor

 

5-HT1D Receptor

 

5-HT1F Receptor

 

體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

293.39

Formula

C16H15D6N3O2

CAS 號(hào)
非標(biāo)記 CAS
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.

儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產(chǎn)品資料
參考文獻(xiàn)
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產(chǎn)品名稱:
Zolmitriptan-d6
目錄號(hào):
HY-B0229S
需求量:
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