4 | 2713172-43-9 | ONO-1078-d4 | 普魯司特-d4 | Isotope-Labeled Compounds | Leukotriene Receptor | Endogenous Metabolite | Inhibitor | inhibitor | inhibit"/>

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  2. Others GPCR/G Protein Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Leukotriene Receptor Endogenous Metabolite
  4. Pranlukast-d4

Pranlukast-d4 是 Pranlukast 氘代物。Pranlukast 是一種高效的競(jìng)爭(zhēng)性的選擇性 leukotriene 拮抗劑。Pranlukast 抑制 [3H]LTE4，[3H]LTD4 和 [3H]LTC4 與肺膜結(jié)合，Ki 分別為 0.63±0.11，0.99±0.19 和 5640±680 nM。

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Pranlukast-d<sub>4</sub>

Pranlukast-d4 Chemical Structure

CAS No. : 2713172-43-9

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規(guī)格 價(jià)格 是否有貨 數(shù)量
1 mg ￥10500
1 - 2 周
5 mg 詢價(jià) 1 - 2 周
10 mg   詢價(jià)  
50 mg   詢價(jià)  

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Other Forms of Pranlukast-d4:

查看 Leukotriene Receptor 亞型特異性產(chǎn)品:

查看 Endogenous Metabolite 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

Pranlukast-d4 is deuterium labeled Pranlukast. Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively.

產(chǎn)品應(yīng)用

1. 該化合物可作為示蹤劑。
2. 該化合物可作為 NMR、GC-MS 或 LC-MS 分析中的內(nèi)標(biāo)品，用于定量分析。
體外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

485.53

Formula

C27H19D4N5O4
CAS 號(hào)
非標(biāo)記 CAS
中文名稱

普魯司特-d4
運(yùn)輸條件

Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

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產(chǎn)品名稱：
Pranlukast-d4
目錄號(hào)：
HY-B0290S1
需求量：
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