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  1. Anti-infection
  2. Fungal
  3. Thymol iodide

Thymol iodide 是麝香草酚的碘衍生物,是溫和防腐劑、殺真菌劑。Thymol iodide 常被用作輪蟲強化培養(yǎng)中的碘源。Thymol iodide 能有效使 Brachionus “Cayman” 輪蟲達到類似橈足類的碘水平,且在儲存過程中能維持較高的碘含量。Thymol iodide 經胸膜內注射給藥 28 天后,不會提升在兔體內誘導胸膜固定術的效果,也不能提升滑石粉漿胸膜固定術的效果。

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Thymol iodide

Thymol iodide Chemical Structure

CAS No. : 552-22-7

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  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

Thymol iodide is an iodine derivative of thymol, serving as a mild preservative and fungicide. Thymol iodide is commonly used as an iodine source in the intensive culture of rotifers. Thymol iodide effectively enables Brachionus "Cayman" rotifers to reach iodine levels similar to those of copepods, and maintains a high iodine content during storage. After 28 days of intrapleural injection of Thymol iodide, it does not enhance the efficacy of inducing pleurodesis in rabbits, nor does it improve the efficacy of talc slurry pleurodesis[1][2].

體內研究
(In Vivo)

Thymol iodide (50 mg;胸膜腔內注射;單次給藥) 與 200 mg/kg talc slurry 聯(lián)合使用時,在以胸膜液體積、大體粘連評分或顯微纖維化評分為評估指標的家兔實驗中,未提升胸膜固定術的效果;在給藥后第 14 天和第 28 天,僅 30% 的受試家兔達到良好的胸膜固定效果[1]。
Thymol iodide (0.3-25.2 g/kg 飼料; 與豐容飼料混合;3 h 豐容) 可通過極低比例的日糧替換 (占總日糧的 0.36-2.03%),將輪蟲的碘含量高效富集至與橈足類相當的水平,且在常溫或低溫條件下儲存長達 18 h 時,仍能維持穩(wěn)定的碘留存率[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: New Zealand white (male)[1]
Dosage: 50 mg (as part of iodized talc slurry with 200 mg/kg talc)
Administration: intrapleural injection; single dose
Result: Recorded mean pleural fluid volume of 2.2 mL at 48 hours post-injection.
Reported mean gross pleurodesis adhesion score of 2.3 and mean microscopic pleural fibrosis score of 2.0 on day 28.
Found 30% of rabbits (3/10) had a good pleurodesis (score 3 or 4) on day 14 and 30% (3/10) on day 28.
Observed no significant differences in pleural fluid characteristics, gross adhesion scores, microscopic inflammation scores, or microscopic fibrosis scores compared to plain talc controls at any time point.
分子量

550.21

Formula

C20H24I2O2

CAS 號
性狀

固體

顏色

Light yellow to yellow

中文名稱

百里碘酚

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性數據
細胞實驗: 

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

Ethanol 中的溶解度 : < 1 mg/mL (insoluble)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

*Thymol iodide is usually formulated as a suspension.

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濃度
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This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start)

C1

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體積 (start)

V1

=
濃度 (final)

C2

×
體積 (final)

V2

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給藥劑量

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純度 & 產品資料
參考文獻
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產品名稱:
Thymol iodide
目錄號:
HY-B1796
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