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  2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. AGN 193109

AGN 193109 (GMP) 是 GMP 級(jí)別的 AGN 193109 (HY-U00449)。GMP 級(jí)別的小分子可用做細(xì)胞療法中的輔助試劑。AGN 193109 是一種專一且高效的視黃酸受體 (RAR) 拮抗劑。AGN 193109 GMP 可逆轉(zhuǎn) TTNPB 誘導(dǎo)的形態(tài)變化和全反式視黃酸 (tRA)/9-順式 RA/13-順式 RA 誘導(dǎo)的 ECE16-1 細(xì)胞增殖抑制。AGN 193109 GMP 是視黃酸中毒的解毒劑，可改善皮膚和粘膜毒性。

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AGN 193109

AGN 193109 Chemical Structure

CAS No. : 171746-21-7

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規(guī)格 價(jià)格 是否有貨 數(shù)量
10 mg ￥9900
In-stock
50 mg ￥28160
In-stock
100 mg   詢價(jià)  
200 mg   詢價(jià)  

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查看 RAR/RXR 亞型特異性產(chǎn)品:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻(xiàn)

生物活性

AGN 193109 (GMP) is AGN 193109 (HY-U00449) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. AGN 193109 is a specific and highly effective retinoic acid receptor (RAR) antagonist[1][2]. AGN 193109 (GMP) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity.

體外研究
(In Vitro)

AGN 193109 (0.1 and 1 μmol/L; 3 w) dose-dependently increases vascular smooth muscle cells (VSMCs) mineralization[1].
AGN 193109 (100?nM; 10 d) induces human pluripotent stem cells (hPSCs) differentiate into olfactory placode cells and neurons[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

392.50

Formula

C28H24O2
CAS 號(hào)
性狀

固體

顏色

White to off-white

運(yùn)輸條件

Shipping with dry ice.
儲(chǔ)存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
純度 & 產(chǎn)品資料
參考文獻(xiàn)

  • 摩爾計(jì)算器

  • 稀釋計(jì)算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
AGN 193109
目錄號(hào)：
HY-U00449G
需求量：
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