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Squalene

SKU: orb1221525

Description

Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil though there are botanical sources as well including rice bran wheat germ and olives. All higher organisms produce squalene including humans. Squalene is an intermediate product in the synthesis of cholesterol and shows several pharmacological properties such as hypolipidemic hepatoprotective cardioprotective antioxidant and antitoxicant activity.

Images & Validation

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Key Properties

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CAS Number111-02-4
MW410.72
Purity>98% (HPLC)
FormulaC30H50
SMILESC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C
TargetEndogenous Metabolite
SolubilityDMSO: 10 mM

Bioactivity

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In Vivo
Animal model: Male mouse models (wild-type, Apoa1-and Apoe-deficient). Dosage: 0.25 g/kg, 1 g/kg. Administration: Fed chow; diets for 11 weeks. Result: Increased high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in mice.

Storage & Handling

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StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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AddaVax | all-trans-Squalene | Nikko Squalane EX | trans-Squalene | Super Squalene | Spinacene

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Squalene (orb1221525)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
$ 80.00
50 mg
$ 110.00
100 mg
$ 150.00
200 mg
$ 200.00
500 mg
$ 310.00
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