Uridine diphosphate glucose

SKU: orb1706057

Description

Uridine diphosphate glucose (UDP-glucose) is a crucial nucleotide sugar that acts as a glucose donor in the biosynthesis of glycogen, glycoproteins, and glycolipids. It is widely used in research on carbohydrate metabolism and serves as an agonist for the P2Y14 receptor in both in vitro and in vivo studies.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number	133-89-1
MW	566.3
Purity	99.75% (May vary between batches)
Formula	C₁₅H₂₄N₂O₁₇P₂
SMILES	O[C@H]1[C@@H](O[C@H](COP(OP(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(=O)O)(=O)O)[C@H]1O)N3C(=O)NC(=O)C=C3
Target	Endogenous Metabolite,P2Y Receptor

Bioactivity

In Vitro	Method: Neutrophils were treated with varying concentrations (0–100 μM) of Uridine diphosphate glucose and incubated for 24 hours. In some groups, PPTN was co-administered. Cell viability and apoptosis were then assessed. Result: Uridine diphosphate glucose treatment decreased neutrophil viability and increased apoptosis, effects that were attenuated by the addition of PPTN.

Storage & Handling

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

Human Endogenous Metabolite, UDP-D-Glucose, Uridine 5′-diphosphoglucose, Uridine diphosphate glucose

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Compound Identifiers

PubChem CID

8629 ↗

Key Properties

No computed properties available.

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