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Menthol

SKU: orb1301551

Description

DL-Menthol is a synthetic or naturally derived compound from mint oils, known for its cooling flavor and local anesthetic properties. It is widely used in research as a TRPM8 channel agonist for studying thermosensation, pain, and inflammation in both in vitro and in vivo models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number1490-04-6
MW156.26
Purity99.88% (May vary between batches)
FormulaC10H20O
SMILESCC(C)C1CCC(C)CC1O
TargetCalcium Channel
SolubilityDMSO:50 mg/mL (319.98 mM)

Bioactivity

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In Vivo
High levels of the major DL-Menthol metabolite, menthol-glucuronide, was observed in the urine of smokers of either menthol or non-menthol cigarettes. The fact that a significant inverse correlation was observed between the levels of urinary menthol-glucuronide and NNAL-N-glucuronide, a major detoxification metabolite of the tobacco carcinogen, NNK, suggests that menthol may be inhibiting the clearance of this important tobacco carcinogen.

Storage & Handling

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StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Calcium Channel, CalciumChannel, DL-Menthol, Menthol

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Key Properties

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No computed properties available.

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Menthol (orb1301551)

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Available Sizes

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1 ml x 10 mM (in DMSO)
$ 90.00
100 mg
$ 90.00
DispatchUsually dispatched within 3-5 working days
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