一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Eledoisin

SKU: orb1219341

Description

Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively.Eledoisin (0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice.

Research Area

Pharmacology & Drug Discovery

Images & Validation

?

Key Properties

?
CAS Number69-25-0
MW1188.4
Purity>98% (HPLC)
FormulaC54H85N13O15S
SMILESCCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3
TargetNeurokinin Receptor
SolubilityH2O:18.15 mg/mL (15.27 mM; Need ultrasonic and warming)

Bioactivity

?
In Vivo
Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice.
In Vitro
Eledoisin (Eledone peptide) increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively.

Storage & Handling

?
StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

?
Eledone peptide

Similar Products

?
  • Eledoisin peptide [orb216568]

    > 95%

    1188.44

    Synthetic

    5 mg,?1 mg,?10 mg
  • Eledoisin Related peptide [orb216569]

    > 95%

    706.96

    Synthetic

    5 mg,?1 mg,?10 mg
  • Eledoisin [orb1679819]

    1188.4

    1 mg,?5 mg,?10 mg
  • Eledoisin Related Peptide [orb1685456]

    706.94

    1 mg,?5 mg
  • Eledoisin trifluoroacetate (69-25-0 free base) [orb1298599]

    98.84% (May vary between batches)

    1302.42

    25 mg,?100 mg,?1 mg,?5 mg,?10 mg,?50 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Eledoisin (orb1219341)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

100 mg
200 mg
500 mg
5 mg
$ 340.00
10 mg
$ 550.00
蒲城县| 城市| 个旧市| 浪卡子县| 湟中县| 阿勒泰市| 内江市| 宁海县| 岳西县| 荔波县| 保定市| 冷水江市| 鸡泽县| 于都县| 平江县| 浮梁县| 荥阳市| 仪陇县| 琼结县| 肥西县| 长海县| 綦江县| 铁岭县| 前郭尔| 遵义市| 昌乐县| 雷山县| 汉川市| 遵化市| 博乐市| 沿河| 池州市| 资阳市| 黑水县| 宣恩县| 阿坝县| 饶阳县| 门源| 抚州市| 抚远县| 梁河县|