Eprinomectin
Catalog No.
BA1268
Eprinomectin (Eprinomectin; MK-397) is an avermectin.
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Eprinomectin (CAS No.: 123997-26-2) is a semi-synthetic macrocyclic lactone avermectin derivative, widely used in veterinary medicine, mainly for the treatment and control of internal and external parasitic infections in cattle. Its mechanism of action primarily involves binding to glutamate-gated chloride channels, causing chloride channels in parasite nerve and muscle cells to open, leading to cellular hyperpolarization and ultimately resulting in parasite paralysis and death. Studies show that Eprinomectin has high activity against a variety of nematode and arthropod parasites; in in vitro experiments, its effective concentration is typically in the nanomolar to low micromolar range. This drug is commonly administered to cattle via topical pour-on or injection, with the specific dose and concentration depending on the experimental design and research objectives.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 914.13 |
| Cas No. | 123997-26-2 |
| Formula | C50H75NO14 |
| Synonyms | MK-397 |
| Solubility | ≥55 mg/mL in DMSO; ≥55.2 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | N-((2S,3R,4S,6S)-6-(((2S,3R,4S,6R)-6-(((2a'E,2a1'R,4'E,5R,6S,6'R,7'R,8'E,11'S,15'S,17a'R,20'R,20a'S)-6-((R)-sec-butyl)-2a1',20'-dihydroxy-5,6',8',19'-tetramethyl-17'-oxo-2a1',5,6,6',10',11',14',15',17',17a',20',20a'-dodecahydro-2'H,7'H-spiro[pyran-2,13'-[ |
| Canonical SMILES | C[C@H]1[C@@H](NC(C)=O)[C@@H](OC)C[C@H](O[C@@H]2[C@H](C)O[C@@H](O[C@@H](/C(C)=C/C[C@@H](C3)OC4(O[C@@H]([C@@H](CC)C)[C@H](C)C=C4)C[C@H]3OC5=O)[C@@H](/C=C/C=C6CO[C@@H]7[C@@]\6(O)[C@H]5C=C(C)[C@H]7O)C)C[C@@H]2OC)O1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
