PF-3450074
Catalog No.
BA1905
PF-3450074 (PF-74) is a specific inhibitor of the HIV-1 coat protein and exhibits broad-spectrum inhibition of isolates
Featured Products
PF-3450074 (PF-74) is a specific inhibitor of HIV-1 capsid proteins and exhibits broad-spectrum inhibition of isolates, displaying sub-micromolar levels of potency (=8-640 nM).PF-3450074 (PF-74) acts at the early stages of HIV-1 infection by directly competing for binding to CPSF6 and NUP153 to inhibit viral replication and block the deamination, assembly and reverse transcription steps of the viral life cycle.CPSF6: nuclear host factor cleavage and polyadenylation specific factor 6; NUP153: nuclear pore protein 153.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 425.52 |
| Cas No. | 1352879-65-2 |
| Formula | C27H27N3O2 |
| Synonyms | PF-74 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |