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Droxidopa

Catalog No.
B1738
Adrenergic receptor agonist
Grouped product items
SizePriceStock Qty
50mg
$308.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Droxidopa (CAS No.: 23651-95-8) is a synthetic amino acid precursor and a prodrug of norepinephrine, mainly used to treat conditions such as neurogenic orthostatic hypotension (NOH). Its mechanism of action involves conversion in vivo to norepinephrine via aromatic L-amino acid decarboxylase (AAAD), thereby increasing norepinephrine levels in the peripheral and central nervous systems, enhancing vasoconstriction, and improving blood pressure regulation. In vitro studies show that Droxidopa can effectively increase the synthesis and release of norepinephrine, with activity typically in the low micromolar range. In cell and animal models, Droxidopa is commonly used to evaluate its effects on blood pressure regulation and neurotransmitter levels, and the doses or concentrations used in experiments typically depend on the experimental design and research objectives.

Chemical Properties

StorageStore at -20°C
M.Wt213.19
Cas No.23651-95-8
FormulaC9H11NO5
Solubility≥5.43 mg/mL in DMSO with ultrasonic; insoluble in EtOH; ≥1.88 mg/mL in H2O with gentle warming and ultrasonic
Chemical Name(2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
Canonical SMILESN[C@@H]([C@@H](c(cc1)cc(O)c1O)O)C(O)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

User Guide

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