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Oxoadipic acid

Catalog No.
C8657
An intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine
Grouped product items
SizePriceStock Qty
50mg
$365.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Email: [email protected]

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Background

2-Oxoadipic acid (CAS No.3184-35-8 ) is an intermediate in the catabolism of L-tryptophan, L-lysine, and hydroxylysine.[1][2]Urinary excretion of 2-oxoadipic acid is increased in patients with α-ketoadipic aciduria, a rare inborn error of metabolism affecting the conversion of 2-oxoadipic acid to glutaryl-coenzyme A (glutaryl-CoA).

Reference:

1. Xia ZW, Inoue Y, Ohse M, Shinka T, Kuhara T. A study on alpha-ketoadipic aciduria by gas chromatographic-mass spectrometry. World J Gastroenterol. 2000 Oct;6(5):766-769. doi: 10.3748/wjg.v6.i5.766. PMID: 11819692; PMCID: PMC4688861.
2. Gray RG, O'Neill EM, Pollitt RJ. Alpha-aminoadipic aciduria: chemical and enzymatic studies. J Inherit Metab Dis. 1980;2(4):89-92. doi: 10.1007/BF01805664. PMID: 6796766.

Chemical Properties

StorageStore at -20°C for 3 years.
M.Wt160.13
Cas No.3184-35-8
FormulaC6H8O5
Synonyms2-Oxoadipic Acid; α-Ketoadipate; 2-Ketoadipic Acid; α-Ketoadipic Acid; α-Oxoadipic Acid
Solubility≥27.8 mg/mL in DMSO; ≥5.14 mg/mL in EtOH with ultrasonic; ≥29.2 mg/mL in H2O
Chemical Name2-oxohexanedioic acid
Canonical SMILESOC(C(CCCC(O)=O)=O)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Chemical structure

Oxoadipic acid
 

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