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Cyclic di-GMP

Catalog No.
B7839
second messenger
Grouped product items
SizePriceStock Qty
500ug
$175.00
In stock
1mg
$335.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Cyclic di-GMP (CAS 61093-23-0) is an intracellular second messenger involved in diverse bacterial physiological processes, including biofilm formation, motility, and pathogenicity. It functions in mammalian cells as an agonist for Stimulator of Interferon Genes (STING), directly binding and activating it to induce innate immune responses. Due to this mechanism, cyclic di-GMP serves as a valuable tool for investigating STING-mediated immune modulation pathways and has research applications in cancer immunotherapy studies, notably enhancing antitumor immunity in metastatic melanoma models.

Chemical Properties

Physical AppearanceA crystalline solid
StorageStore at -20°C
M.Wt690.41
Cas No.61093-23-0
Formula C20H24N10O14P2
Solubilityinsoluble in DMSO; insoluble in EtOH; ≥20.85 mg/mL in H2O
Chemical Name9,9'-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidodecahydrodifuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl)bis(2-amino-1H-purin-6(9H)-one)
Canonical SMILESO=C1NC(N)=NC2=C1N=CN2[C@H](O[C@@]([C@@]3([H])OP(O)(OC[C@]([C@@]4([H])OP5(O)=O)(O[C@@H](N6C(N=C(N)NC7=O)=C7N=C6)[C@@H]4O)[H])=O)(CO5)[H])[C@@H]3O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Cyclic di-GMP
 

User Guide

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