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Dibucaine

Catalog No.
B3373
Local anesthetic
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
500mg
$55.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Dibucaine is an amin amide local anesthetic [1].

Dibucaine has shown the ability to block the fast axonal transport of proteins. In addition, a 0.5 mM concentration of Dibucaine has been revealed to inhibit transport approximately as much as dose a 1mM concentration of tetracaine. Furthermore, 1mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 92%, and 0.5mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 72% in the experiments examined the effect on fast axonal transport of 3H-proteins [1].

References:
[1] Lavoie PA. Block of fast axonal transport in vitro by the local anesthetics dibucaine and etidocaine. J Pharmacol Exp Ther. 1982 Oct;223(1):251-6.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt343.46
Cas No.85-79-0
FormulaC20H29N3O2
Solubilityinsoluble in H2O; ≥16.45 mg/mL in DMSO; ≥27.1 mg/mL in EtOH
Chemical Name2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Canonical SMILESCCCCOc1nc(cccc2)c2c(C(NCCN(CC)CC)=O)c1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

User Guide

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