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Aceclofenac

Catalog No.
B3475
non-steroidal anti-inflammatory drug
Grouped product items
SizePriceStock Qty
1g
$60.00
Ship with 10-15 days
5g
$118.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Aceclofenac (CAS No.: 89796-99-6) is a non-steroidal anti-inflammatory drug (NSAID), mainly used to relieve pain and inflammation caused by diseases such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. Its mechanism of action is primarily through inhibition of cyclooxygenase-2 (COX-2) activity, reducing the production of prostaglandin E2 (PGE2), interleukin-1β (IL-1β), and tumor necrosis factor (TNF), thereby exerting anti-inflammatory and analgesic effects. In addition, Aceclofenac can inhibit nitric oxide production in human articular chondrocytes and, by reducing the expression of L-selectin (CD62L), interfere with neutrophil adhesion to endothelial cells. In in vitro studies, Aceclofenac shows activity at nanomolar to low micromolar levels. In cell and animal models, Aceclofenac is often used to evaluate its anti-inflammatory and analgesic effects, and the doses or concentrations used in experiments typically depend on the experimental design and research objectives.

Chemical Properties

StorageStore at -20°C
M.Wt354.18
Cas No.89796-99-6
FormulaC16H13Cl2NO4
Solubility≥46.4 mg/mL in DMSO; ≥18.45 mg/mL in EtOH; insoluble in H2O
Chemical Name2-(2-(2-((2,6-dichlorophenyl)amino)phenyl)acetoxy)acetic acid
Canonical SMILESOC(COC(Cc(cccc1)c1Nc(c(Cl)ccc1)c1Cl)=O)=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Aceclofenac
 

User Guide

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