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DBCO-C6-NHS ester

DBCO-C6-NHS ester


DBCO-C6-NHS ester is an amine-reactive compound, which can be used to modify an amine-containing molecule in organic media. This reagent isn't soluble in aqueous media. The extended 6-carbon atom spacer arm improves solubility in commonly used organic solvents including dichloromethane, chloroform, THF, and ethyl acetate and it also improves derivatization efficiency and stability of conjugates. DBCO is commonly used for copper-free Click Chemistry reactions. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22447
    • Unit
    • Price
    • Qty
    • 100 MG
    • $200.00
    • 250 MG
    • $390.00
    • 500 MG
    • $680.00
    • 1 G
    • $1050.00

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Product Citations


  1. Samanta, A., Malle, M. G., Tsang, E., Omer, M., Skaanning, M. K., Kjems, J., & Gothelf, K. V. (2025). Bacteriophage-Mimetic DNA Origami Needle for Targeted Membrane Penetration and Cytosolic Cargo Delivery. bioRxiv, 2025-06.
    https://www.biorxiv.org/content/10.1101/2025.06.16.659898v1.abstract
  2. Toni Kline, Qun Yin, BAJJURI Krishna. Hemiasterlin derivatives for conjugation and therapy. (HK40063945A)
    https://patents.google.com/patent/HK40063945A/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=32
  3. Toni Kline, Qun Yin, Krishna Bajjuri. Hemiasterlin derivatives for conjugation and therapy. (US20240254163A1)
    https://patents.google.com/patent/US20240254163A1/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=16
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