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Tetrazine-PEG5-NHS ester

Tetrazine-PEG5-NHS ester


Tetrazine-PEG5-NHS Ester is a PEG linker containing a tetrazine group and an NHS ester which is very reactive with amine(NH2)-containing molecule. Tetrazine enable fast click reaction with TCO (trans-cycloctene). The chemical stability of tetrazines is lower compared to methyltetrazines, but it is in acceptable range and thus can be applied for many applications. Please contact us for GMP-grade inquiries.

Molecular structure of the compound BP-22681
    • Unit
    • Price
    • Qty
    • 10 MG
    • $173.00
    • 25 MG
    • $292.00
    • 100 MG
    • $827.00

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Product Citations


  1. Browne, A. S., Fang, J., Elsharkawy, A., Jia, T., Reboli, E., Luo, Y., ... & Iyer, S. S. (2025). Multilayer Fluorescent Immunoassay for Early and Sensitive Dengue Virus Detection Using Host and Viral Biomarkers. Bioconjugate Chemistry.
    https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.5c00153
  2. Dinesen A, Andersen VL, Elkhashab M, Pilati D, Bech P, Fuchs E, Samuelsen TR, Winther A, Cai Y, Märcher A, Wall A, Omer M, Nielsen JS, Chudasama V, Baker JR, Gothelf KV, Wengel J, Kjems J, Howard KA. An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjug Chem. 2024 Jan 17. doi: 10.1021/acs.bioconjchem.3c00491. Epub ahead of print. PMID: 38231391.
    https://pubs.acs.org/doi/10.1021/acs.bioconjchem.3c00491
  3. Dinesen, A., Andersen, V. L., Elkhashab, M., Pilati, D., Bech, P., Fuchs, E., ... & Howard, K. A. (2024). An Albumin-Holliday Junction Biomolecular Modular Design for Programmable Multifunctionality and Prolonged Circulation. Bioconjugate Chemistry.
    https://pubs.acs.org/doi/abs/10.1021/acs.bioconjchem.3c00491
  4. Gandhi, S., Shaulli, X., Fock, J., Scheffold, F., & Marie, R. (2024). IgG and IgM differentiation in a particle-based agglutination assay by control over antigen surface density. APL bioengineering, 8(2).
    https://pubs.aip.org/aip/apb/article/8/2/026124/3298169
  5. Kenneth Alan Howard, Diego PILATI. Albumin conjugated to cpg oligodeoxynucleotides as super-boosters of immune response. (WO2024089258A1)
    https://patents.google.com/patent/WO2024089258A1/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=18
  6. Nagao, K., Vargas Paniagua, E., Lei, K., Beckham, J. L., Worthington, P., Manthey, M., ... & Anikeeva, P. (2025). Adeno-associated viruses escort nanomaterials to specific cells and tissues. bioRxiv, 2025-04.
    https://doi.org/10.1101/2025.04.04.647267
  7. Polina Olegovna Anikeeva, Keisuke Nagao. Spatially Localized Gene Delivery of Adeno-Associated Viruses. (US20250179521A1)
    https://patents.google.com/patent/US20250179521A1/en?q=(BROADPHARM)&oq=BROADPHARM&sort=new&page=8
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