Tyrphostin AG 490
Catalogue Number BIT1100
Synonym(s): N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide, 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(benzyl)-2-propenamide, AG 490, Tyrphostin B42
- CAS Number
134036-52-5
- Commodity Code
2926907090
- MDL Number
MFCD00209833
- Notes
- Specific and potent JAK-2 protein tyrosine kinase inhibitor. Also inhibits EGF receptor autophosphorylation, with an IC50 of 100 nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Biochem. Pharmacol. 40: 913-918 (1990).
- Formula Weight
- 294.30 g/mol
- Melting Point
- 213-225 °C
- Chemical Hazard
- Toxic/Harmful/Irritant
- GHS
-
- Hazard Statements
-
H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H312+H332: Harmful in contact with skin or if inhaled
- Precautionary Statements
-
P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c: hazard.P280: Wear {{{0|||message=<specify protection equipment>|||default=protective gloves/protective clothing/eye protection/face protection|||filter=(_)?P280_PROT_EQUIPMENT_.+}}}.
P301+P310: IF SWALLOWED: Immediately call {{{0|||message=<specify appropriate c
- MSDS
- Typical Batch COA
- Request COA Information
- Request batch specific COA here
Size
UK Stock
UK stock will be shipped internationally
US Stock
US stock is for US shipping only
Price
Quantity
Add to Basket