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QCC37871 - TCS 184

QCC37871

TCS 184

TCS 184 is a synthetic glycogen synthase kinase 3 (GSK-3) inhibitor that has been shown to increase the level of glycogen in cultured cells. TCS 184 was also found to inhibit glycogen synthase activity and decrease glucose uptake. The enzyme GSK... Read More
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  Strictly for Research Purposes only. Not for Personal or Veterinary use.

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CAS No
[1315378-71-2]
Product Code
QCC37871
MOL file
Chemical Formula
C58H96N20O20S
Molecular Weight
1,425.6 g/mol
Smiles
CC(C(C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCSC)C(=O)NC(CCCN=C(N)N)C(=O)N2CCCC2C(=O)NC(CO)C(=O)NCC(=O)NC(CO)C(=O)NC(CCCN=C(N)N)C(=O)N)N)O
TCS 184 is a synthetic glycogen synthase kinase 3 (GSK-3) inhibitor that has been shown to increase the level of glycogen in cultured cells. TCS 184 was also found to inhibit glycogen synthase activity and decrease glucose uptake. The enzyme GSK-3 is involved in the assembly of glycogen, and inhibiting this enzyme leads to increased levels of glycogen. TCS 184 can be used for culturing cells as it does not require oxygen for its synthesis. This drug can be used for short-term studies as it does not have long-term effects on cells. TCS 184 also inhibits GSK-3, which is involved in the regulation of endoderm and extraembryonic tissue development during early embryonic development.
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TSE / BSE Statement
TSE-BSE declaration TCS 184 QCC37871
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Retest Statement TCS 184 QCC37871
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