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G-6100 - Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride

G-6100

Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride

Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride (Gly-Gly-AMC) is a fluorescent compound that can be used as a probe for the transfer of glycine in the brain. Gly-Gly-AMC binds to Langerhans cells and is transferred by an anterograde axonal... Read More
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The product G-6100 is available on a large scale and is intended for use in the chemical, diagnostic, pharmaceutical and related industries.

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Research & Development
CAS No
[191723-65-6]
Product Code
G-6100
MDL No
MFCD00182090
MOL file
Chemical Formula
C14H16ClN3O4
Molecular Weight
325.75 g/mol
Smiles
CC(C1=CC=C(NC(CNC(CN)=O)=O)C=C1O2)=CC2=O.Cl
Long Term Storage
store at <-15°C
Storage
store at <-15°C
Precautionary Statement Code
P261, P262
Harmonized Tariff Codes
Switzerland: 29329900 - USA: 2932200500 - Slovakia: 2932990080 -
Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride (Gly-Gly-AMC) is a fluorescent compound that can be used as a probe for the transfer of glycine in the brain. Gly-Gly-AMC binds to Langerhans cells and is transferred by an anterograde axonal transport mechanism from the peripheral nervous system to the central nervous system. The binding of Gly-Gly-AMC to Langerhans cells has been shown to activate them, which induces the release of inflammatory mediators into the surrounding tissue. This activity may be due to increased levels of calcium ions, which are known to induce exocytosis in these cells. Glycine is also involved in depression and other mental disorders, as well as muscle and brain activity.
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