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FP136709 - 2-[(Phenylsulfonyl)amino]benzoic acid

FP136709

2-[(Phenylsulfonyl)amino]benzoic acid

2-[(Phenylsulfonyl)amino]benzoic acid is a white crystalline solid that is soluble in water and ethanol. It has a melting point of 176°C and a boiling point of 280°C. 2-[(Phenylsulfonyl)amino]benzoic acid binds to DNA by an intercalative mecha... Read More
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CAS No
[34837-67-7]
Synonyms
benzoic acid, 2-[(phenylsulfonyl)amino]-
Product Code
FP136709
MDL No
MFCD00429933
MOL file
Chemical Formula
C13H11NO4S
Molecular Weight
277.3 g/mol
Smiles
C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)O
Long Term Storage
store at 10°C - 25°C
Storage
store at 10°C - 25°C
Harmonized Tariff Codes
Switzerland: 29359090 - USA: 2935907500 - Slovakia: 2935909059 - UK: 2935909000 - China: 2935909009
2-[(Phenylsulfonyl)amino]benzoic acid is a white crystalline solid that is soluble in water and ethanol. It has a melting point of 176°C and a boiling point of 280°C. 2-[(Phenylsulfonyl)amino]benzoic acid binds to DNA by an intercalative mechanism, forming covalent bonds with the bases on the DNA. This binding prevents the DNA from unwinding during replication and transcription, thus inhibiting the synthesis of RNA and protein. The dimers form between two molecules of 2-[(Phenylsulfonyl)amino]benzoic acid, due to hydrogen bonding between the carboxylic acid groups. The crystal structure has been determined for this compound as centrosymmetric with space group P2 1 /c. A benzene ring is found in the molecule, which can form a pyridine ring when exposed to heat or
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