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FD22249 - (S)-4',7-Dimethyl equol

FD22249

(S)-4',7-Dimethyl equol

(S)-4',7-Dimethyl equol is an isoflavandiol, which is a metabolite of the soy isoflavone daidzein. It is produced in the human gut by bacterial metabolism, provided the individual has the appropriate intestinal microbiota capable of this transfo... Read More
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  Strictly for Research Purposes only. Not for Personal or Veterinary use.

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CAS No
[3722-56-3]
Synonyms
(S)-(-)-4',7-Dimethoxyisoflavan
Product Code
FD22249
MDL No
MFCD18252484
MOL file
Chemical Formula
C17H18O3
Molecular Weight
270.32 g/mol
Smiles
COC1=CC=C(C=C1)[C@@H]2CC3=C(C=C(C=C3)OC)OC2
(S)-4',7-Dimethyl equol is an isoflavandiol, which is a metabolite of the soy isoflavone daidzein. It is produced in the human gut by bacterial metabolism, provided the individual has the appropriate intestinal microbiota capable of this transformation. The compound exhibits estrogenic activity, primarily due to its structural similarity to the endogenous hormone 17β-estradiol, allowing it to bind to estrogen receptors.

Studies indicate that (S)-4',7-Dimethyl equol can modulate hormonal activity, potentially offering benefits such as alleviating menopausal symptoms, supporting bone health, and reducing the risk of hormone-dependent cancers. Its selective action on different estrogen receptors suggests a complex mechanism that may provide a balance between estrogenic and anti-estrogenic effects, depending on the tissue context. Such properties make it a molecule of significant interest in the field of endocrine research. Applications may extend to nutritional supplements and therapeutic agents aiming to exploit its moderated estrogenic effects for beneficial health outcomes.
  1. Heemstra, J. M., et al., Org. Lett., 8, 5441(2006).
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TSE / BSE Statement
TSE-BSE declaration (S)-4',7-Dimethyl equol FD22249
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