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SBA13576 - 4-(3-Chlorophenyl)-3-thiosemicarbazide

SBA13576

4-(3-Chlorophenyl)-3-thiosemicarbazide

4-(3-Chlorophenyl)-3-thiosemicarbazide is a hydrazone that has been shown to have antibacterial and anticancer activities. This compound binds to DNA, which leads to the inhibition of bacterial growth and cancer cell proliferation. 4-(3-Chloroph... Read More
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  Strictly for Research Purposes only. Not for Personal or Veterinary use.

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CAS No
[42135-76-2]
Product Code
SBA13576
MDL No
MFCD00041287
MOL file
Chemical Formula
C7H8ClN3S
Molecular Weight
201.68 g/mol
Smiles
C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O.Cl
Flash Point
130 °C
UN Number
UN2811
E Code
E1
Pack Group
III
Class
6.1
4-(3-Chlorophenyl)-3-thiosemicarbazide is a hydrazone that has been shown to have antibacterial and anticancer activities. This compound binds to DNA, which leads to the inhibition of bacterial growth and cancer cell proliferation. 4-(3-Chlorophenyl)-3-thiosemicarbazide has been shown to inhibit the growth of P. aeruginosa in vitro by binding to the DNA gyrase and topoisomerase IV enzymes, preventing them from maintaining the integrity of bacterial DNA. Molecular modeling studies have shown that this compound binds preferentially to human astrocytes rather than cancer cells. It is also an anhydrous potassium carbonate salt that is soluble in water, alcohols, ethers, and acetones.
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TSE / BSE Statement
TSE-BSE declaration 4-(3-Chlorophenyl)-3-thiosemicarbazide SBA13576
Retest Statement
Retest Statement 4-(3-Chlorophenyl)-3-thiosemicarbazide SBA13576
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