Adamantylanisole is a phenacyl derivative that can be synthesized in two steps. Adamantylanisole is an analog of adamantane that has been functionalized with a phenacyl group, azido group and cyclohexyl group. The adamantanes have been modified to contain fluorides or fluorinated functional groups. Adamantylanisole has shown anti-inflammatory effects in the CNS by inhibiting the synthesis of prostaglandin E2 (PGE2) and nitric oxide (NO). It also has been used as a probe for designing drugs against Alzheimer's disease and Parkinson's disease.

1. Saito, S., et al., Chem. Pharm. Bull., 39, 2718 (1991)

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• groups, adamantane, synthesized, methyl, functional groups, adamantanes, functionalized, functional, group, analog, acetate, azido, phenacyl, scheme, skeleton, fluorinated, memantine, azido group, fluorides, cyclohexyl, synthesis, alkoxy, Show less