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EAA61663 - 2-prop-2-ynoxyisoindoline-1,3-dione

EAA61663

2-prop-2-ynoxyisoindoline-1,3-dione

2-Prop-2-ynoxyisoindoline-1,3-dione is a multifunctional pyridine derivative with potential anticancer activity. It has been shown to inhibit HDAC and panobinostat, an inhibitor of histone deacetylase. 2-Prop-2-ynoxyisoindoline-1,3-dione has a s... Read More
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CAS No
[4616-63-1]
Product Code
EAA61663
MDL No
MFCD00005890
MOL file
Chemical Formula
C11H7NO3
Molecular Weight
201.18 g/mol
Smiles
C#CCON1C(=O)C2=CC=CC=C2C1=O
Flash Point
150 °C
2-Prop-2-ynoxyisoindoline-1,3-dione is a multifunctional pyridine derivative with potential anticancer activity. It has been shown to inhibit HDAC and panobinostat, an inhibitor of histone deacetylase. 2-Prop-2-ynoxyisoindoline-1,3-dione has a solubility of less than 20 mg/mL in most solvents and is insoluble in water. This compound has been shown to have a low yield when synthesized from 2,6-dichloropyridine. These properties are advantageous for cell culture studies because they allow for the detection of changes in cellular morphology and the frequency of cell division. 2-Prop-2-ynoxyisoindoline-1,3-dione also has an activated aromatic ring that can be used as a prodrug to activate other compounds that need activation at this site (e.g., transition metals).
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TSE / BSE Statement
TSE-BSE declaration 2-prop-2-ynoxyisoindoline-1,3-dione EAA61663
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Retest Statement 2-prop-2-ynoxyisoindoline-1,3-dione EAA61663
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