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NB09916 - 5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt

NB09916

5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt

5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcom... Read More
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CAS No
[51432-32-7]
Synonyms
5-BrdUMP. 2Na
Product Code
NB09916
MDL No
MFCD00057406
MOL file
Chemical Formula
C9H12BrN2O8PNa2
Molecular Weight
433.06 g/mol
Smiles
C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)Br)COP(=O)([O-])[O-])O.[Na+].[Na+]
Long Term Storage
store at 10°C - 25°C
Storage
store at 10°C - 25°C
Hazard Statement Code
H351
Precautionary Statement Code
P201, P202, P280, P308+P313, P501
GHS Information
GHS Code GHS08
Harmonized Tariff Codes
Switzerland: 29349900 - USA: 2934920000 - Slovakia: 2934999090 - UK: 2934999000 - China: 2934999099
5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.
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CoA (Example)
NB09916 CofA
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