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IS27833 - Simvastatin 4'-methyl ether

IS27833

Simvastatin 4'-methyl ether

Simvastatin 4'-methyl ether is a metabolite of simvastatin. It is an impurity in the drug product and can be used as an analytical standard for HPLC. It is not a drug product or a pharmaceutical ingredient, but it can serve as an impurity standa... Read More
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CAS No
[864357-88-0]
Synonyms
2,2-Dimethyl-butanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2 -yl]ethyl]-1-naphthalenyl ester
Cholestat methyl ether
Product Code
IS27833
MOL file
Chemical Formula
C26H40O5
Molecular Weight
432.59 g/mol
Smiles
CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@@H](CC(=O)O3)OC)C

Simvastatin 4'-methyl ether is a metabolite of simvastatin. It is an impurity in the drug product and can be used as an analytical standard for HPLC. It is not a drug product or a pharmaceutical ingredient, but it can serve as an impurity standard for pharmacopoeia.

  1. Vuletic, M., et al., J. Pharm. Biomed. Anal., 37, 715 (2005)

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Specification
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MSDS
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TSE / BSE Statement
TSE-BSE declaration Simvastatin 4'-methyl ether IS27833
Retest Statement
Retest Statement Simvastatin 4'-methyl ether IS27833
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