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ID106394 - 4-Dehydroxy-4-dimethylhydroxysilyl entecavir

ID106394

4-Dehydroxy-4-dimethylhydroxysilyl entecavir

4-Dehydroxy-4-dimethylhydroxysilyl entecavir is an impurity standard for the drug product Entecavir. It is a synthetic drug that inhibits the production of human immunodeficiency virus (HIV) by binding to reverse transcriptase and blocking its a... Read More
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  Strictly for Research Purposes only. Not for Personal or Veterinary use.

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CAS No
[870614-82-7]
Synonyms
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydimethylsilyl)-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
Product Code
ID106394
MOL file
Chemical Formula
C14H21N5O3Si
Molecular Weight
335.43 g/mol
Smiles
C[Si](C)(C1C[C@@H](C(=C)[C@@H]1CO)N2C=NC3=C2N=C(NC3=O)N)O
4-Dehydroxy-4-dimethylhydroxysilyl entecavir is an impurity standard for the drug product Entecavir. It is a synthetic drug that inhibits the production of human immunodeficiency virus (HIV) by binding to reverse transcriptase and blocking its activity. The metabolite of 4-dehydroxy-4-dimethylhydroxysilyl entecavir, entecavir, is also used as a treatment for HIV. Synthetic 4-dehydroxy-4-dimethylhydroxysilyl entecavir is used in clinical trials as a drug product and metabolite of entecavir to measure the concentration of the active ingredient in plasma and other body fluids. 4DDSILENT has been shown to have antiviral properties against HIV due to its ability to inhibit transcriptional activation by binding to reverse transcriptase, which prevents RNA from being synthesized into DNA.
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MSDS
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TSE / BSE Statement
TSE-BSE declaration 4-Dehydroxy-4-dimethylhydroxysilyl entecavir ID106394
Retest Statement
Retest Statement 4-Dehydroxy-4-dimethylhydroxysilyl entecavir ID106394
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