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Ziconotide

  Cat. No.:  DCC5609   Featured
Chemical Structure
107452-89-1
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More than 5000 active chemicals with high quality for research!
Field of application
Atypical analgesic agent for the amelioration of severe and chronic pain
Cas No.: 107452-89-1
Chemical Name: Ziconotide Polyacetate
Synonyms: Ziconotide acetate;Ziconotide;Ziconotide Polyacetate;ω-Conotoxin MVIIA;o-Conotoxin MVIIA;Omega-conotoxin MVIIA;snx111;SNX-111,Ziconotide;18,19,65,66,81,82-Hexathia-3,6,9,12,15,22,25,28,31,34,37,40,43,46,49,52,55,58,61,70,73,76,79,84-tetracosaazatricyclo[40.37.4.221,68]pentaoctacontane,cyclic peptide deriv.;Omegaconopeptide MVIIA (Conus);Prialt;w-Conopeptide MVIIA (Conus);w-Conotoxin M VIIA (reduced),cyclic (1?16),(8?20),(15?25)-tris(disulfide);OMEGA-CGTX MVII A;Ziconotide [USAN:INN];omega-conopeptide MVIIA;65: PN: WO2006116156 SEQID: 65 claimed protein;SNX 111;SNX-111, Ziconotide;MFCD00145036;CS-0015087;CHEBI:135912;DRG-0250;GTPL2536;HS-2032;DTXCID901323852;7I64C51O16;DTXSID60883174;omega-Conotoxin mviia, conus magus;Y-100004;150770-63-1;Ziconotida;107452-89-1;L-Cysteinyl-L-lysylglycyl-L-lysylglycyl-L-alanyl-L-lysyl-L-cysteinyl-L-seryl-L-arginyl-L-leucyl-L-methionyl-L-tyrosyl-L-alpha-aspartyl-L-cysteinyl-L-cysteinyl-L-threonylglycyl-L-seryl-L-cysteinyl-L-arginyl-L-serylglycyl-L-lysyl-L-cysteinamide cyclic (1-16),(8-20),(15-25)-tris(disulfide);ziconotidum;CHEBI:142406;AC-8938;ZICONOTIDE (MART.);omega-Conotoxin M VIIA;H-Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cy;HY-P0062;omega-Conopeptide MVIIA (Conus);.omega.-conotoxin m viia;omega-Conotoxin M VIIA (reduced), cyclic (1-16),(8-20),(15-25)-tris(disulfide);omega-Conotoxin MVIIA, >=95% (HPLC);N02BG08;SNX-111;AKOS015994641;HSDB 7609;UNII-7I64C51O16;CHEMBL4594214;NS00068028;?-Conotoxin M VIIA Acetate; ?-Conopeptide MVIIA Acetate; Prialt Acetate; SNX 111;;AT42420
SMILES: S(C)CC[C@H]1C(N[C@H](C(N[C@H](C(N[C@@H]2C(N[C@@H]3C(N[C@H](C(NCC(N[C@@H](CO)C(N[C@H](C(N[C@H](C(N[C@@H](CO)C(NCC(N[C@H](C(N[C@H](C(N)=O)CSSC2)=O)CCCCN)=O)=O)=O)CCCNC(=N)N)=O)CSSC[C@@H](C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(N1)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)NC([C@H](CCCCN)NC([C@H](C)NC(CNC([C@H](CCCCN)NC(CNC([C@H](CCCCN)NC([C@H](CSSC3)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](C)O)=O)=O)=O)CC(=O)O)=O)CC1C=CC(=CC=1)O)=O
Formula: C102H172N36O32S7
M.Wt: 2639.13409137726
Purity: 98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC31079 Abarelix Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth.
DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC80858 UCB1244283 Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A.
DC79856 EVT0185 EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. EVT0185 is converted to a CoA thioester in the liver by SLC27A2 and interacts with the CoA-binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC50 of 2.5 μM. EVT0185 can phenocopy the immune and antitumour effects of genetic ACLY deletion. EVT0185 can increase tumour-infiltrating B cells and chemokine CXCL13 levels. EVT0185 can be used for the research of cancer, such as hepatocellular carcinoma (HCC).
DC79609 NCGC00685960 NCGC00685960 is a Nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 < 10 ?nM. NCGC00685960 has potent antitumor activity. NCGC00685960 increases H3K27 trimethylation levels in ovarian cancer cells and inhibits α-SMA expression in NNMT-expressing ovarian fibroblasts. NCGC00685960 reduces 1-MNA levels, reverses SAM and H3K27 hypomethylation and significantly impairs collagen contractility in cancer-associated fibroblasts (CAFs). NCGC00685960 can be used for cancers research.
DC79252 MGD-22 MGD-22, a molecular glue, is an orally active IKZF1/2/3 degrader with DC50 values of 8.33 nM, 9.91 nM, and 5.74 nM, respectively. MGD-22 exhibits extremely potent anti-proliferative activity against diverse hematological cancer cells. MGD-22 induces apoptosis in cancer cells. MGD-22 demonstrates potent anti-tumor efficacy in mice bearing NCI-H929 xenografts or WSU-DLCL-2 xenografts. MGD-22 can be used for the study of hematological cancers, including multiple myeloma (MM), acute myeloid leukemia (AML), and diffuse large B-cell lymphoma (DLBCL).
DC79112 Simepdekinra Simepdekinra (Compound 221) is a IL-17A modulator with IC50s ≤10 ?nM and 10-100 nM for IL-17A/A HEK-Blue and IL-17A/F HEK-Blue cells. Simepdekinra can be used for inflammatory diseases such as psoriasis, ankylosing spondylitis and psoriatic arthritis research.
DC78751 RSL3-NH2 RSL3-NH2 is a GPX4 inhibitor and Ferroptosis inducer. RSL3-NH2 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs).
DC78592 ZINC13000658 ZINC13000658 is a METTL inhibitor. ZINC13000658 exhibits significant anti proliferative activity in various cells and can induce G1 phase cell cycle arrest and apoptosis such as HepG2 (IC50 = 5.632 μM) and SNU-449 (IC50 = 6.184 μM) cells. ZINC13000658 may be related to the inhibition of the activity of multiple methyltransferases such as METTL1, 3, 6, 16, 18, etc. ZINC13000658 can be used for research on various types of cancer.
DC78326 XL-3156 XL-3156 is a potent, selective, and cross-species cGAS inhibitor. XL-3156 can simultaneously occupy both allosteric and orthosteric sites, and inhibit the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of autoimmune diseases, inflammatory conditions and other diseases.
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