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| Cas No.: | 566-48-3 |
| SMILES: | OC1C(=O)CCC2(C)C=1CCC1C2CCC2(C)C1CCC2=O |
| Formula: | C19H26O3 |
| M.Wt: | 302.41 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Formestane(CGP-32349; 4-OHA) is a selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer.Formestane (Lentaron) is a type I, steroidal aromatase inhibitor. formestane is an effective and well tolerated addition to the therapeutic options available for the treatment of postmenopausal women with advanced breast cancer. Formestane (4-hydroxyandrostenedione) is an aromatase inhibitor which significantly reduces plasma levels of estrogen and has shown antitumour activity in postmenopausal women with breast cancer. Formestane is well tolerated by the majority of patients; adverse events rarely necessitate cessation of therapy. Formestane is effective and well tolerated as first-line endocrine therapy for advanced disease. |