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Radafaxine (hydrochloride)

  Cat. No.:  DC9513   Featured
Chemical Structure
106083-71-0
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Field of application
Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat
Cas No.: 106083-71-0
Chemical Name: 2-Morpholinol,2-(3-chlorophenyl)-3,5,5-trimethyl-, hydrochloride (1:1), (2S,3S)-
Synonyms: 2-Morpholinol,2-(3-chlorophenyl)-3,5,5-trimethyl-, hydrochloride (1:1), (2S,3S)-;(2S,3S)-Hydroxybupropion hydrochloride;(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol,hydrochloride;GW-353162A;(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride;(2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride;GW 353162;Radafaxine hydrochloride;SS-hydroxybupropion hydrochloride;GW 353162A;Bupropion Morpholinol IMpurity;Bupropion Morpholinol IMpurity (HCl Salt);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;Radafaxine (hydrochloride)
SMILES: Cl.ClC1=CC(=CC=C1)C2(O)C(C)NC(C)(C)CO2
Formula: C13H18NO2Cl.HCl
M.Wt: 292.20146
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.
References: [1]. Xu H, et al. Stereoselective analysis of hydroxybupropion and application to drug interaction studies. Chirality. 2007 Mar;19(3):163-70. [2]. Bondarev ML, et al. Behavioral and biochemical investigations of bupropion metabolites. Eur J Pharmacol. 2003 Aug 1;474(1):85-93.
Cat. No. Product name Field of application
DC9513 Radafaxine (hydrochloride) Radafaxine Hcl(BW-306U; GW-353162A) is a potent metabolite of bupropion; selective for inhibiting the reuptake of norepinephrine over dopamine; DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulat
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