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  1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Atrial natriuretic factor (1-28) (human, porcine)

Atrial natriuretic factor (1-28) (human, porcine)  (Synonyms: Atrial natriuretic peptide (1-28))

目錄號: HY-P2281
一鍵復制產品信息
產品使用指南 技術支持

Atrial natriuretic factor (1-28) (human, porcine) 通過增加鈉和尿液排泄表現出降血壓的活性。Atrial natriuretic factor (1-28) (human, porcine) 通過抑制促阿片黑素皮質素 (POMC) 表達來抑制垂體促腎上腺皮質激素 (ACTH) 和 β-內啡肽的釋放。Atrial natriuretic factor (1-28) (human, porcine) 增加 RMIC 細胞中的 cGMP 水平,IC50 為 1.2 nM。

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Atrial natriuretic factor (1-28) (human, porcine)

Atrial natriuretic factor (1-28) (human, porcine) Chemical Structure

CAS No. : 91917-63-4

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規(guī)格 價格 是否有貨 數量
500 μg ¥5225
3 - 4 周
1 mg 詢價 3 - 4 周
5 mg   詢價  
10 mg   詢價  

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Customer Review

Other Forms of Atrial natriuretic factor (1-28) (human, porcine):

MCE 顧客使用本產品發(fā)表的 1 篇科研文獻

查看 Endogenous Metabolite 亞型特異性產品:

  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

Atrial natriuretic factor (1-28) (human, porcine) exhibits blood pressure lowering activity by increasing sodium and urine excretion. Atrial natriuretic factor (1-28) (human, porcine) inhibits the release of pituitary adrenocorticotropic hormone (ACTH) and beta-endorphin through inhibition of pro-opiomelanocortin (POMC) expression. Atrial natriuretic factor (1-28) (human, porcine) increases cGMP levels in RMIC cells with an IC50 of 1.2 nM[1][2][3].

體外研究
(In Vitro)

ANF-(1-28) markedly increaseS guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10(6) cells [50% effective dosage (ED50) = 1.2 nM][1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

體內研究
(In Vivo)

ANF-(1-28) (0.5 μg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3080.46

Formula

C127H205N45O39S3

CAS 號
Sequence

Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr

Sequence Shortening

SLRRSSCFGGRMDRIGAQSGLGCNSFRY

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產品資料
參考文獻
  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產品名稱:
Atrial natriuretic factor (1-28) (human, porcine)
目錄號:
HY-P2281
需求量:
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