Anti-TSLP antibody (humanized ,1A1A）
Anti-TSLP抗體
PRODUCT DETAILS
Product Name Anti-TSLP antibody
Species Reactivity Human, Primate
Source Recombinant chimeric antibody (mouse)
Isotype IgG1-kappa (human)
Expression System HEK 293 cell
Purification Protein A purified
Label Unconjugated
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose
Reconstitution Centrifuge vial prior to opening vial. Add 0.5 mL sterile water or 0.01M PBS (pH7.2) at 0.4 mg/mL. Gently pipet solution down the sides of the vial.
DO NOT VORTEX.
Please note: For research use only. Not for diagnostic or therapeutic use.
SHIPPING & STROAGE
Shipping Lyophilized product is shipped at ambient temperature.
Storage Upon receipt, store immediately at -20 to -70°C:12 months from date of receipt. After reconstitution under sterile conditions: 2 to 8 °C or 1 month or -20 to -70°C for 6 months.
Avoid freeze-thaw cycles.
APPLICATIONS
Item Description Data Examples
Immunoassay Ligand Binding-Sandwich ELISA
In a sandwich ELISA, a concentration of 1 μg/mL (100 μL/well) of recombinant human TSLP (Cat.#: 0721061) will be detected by the Anti-TSLP Ab (Cat.#: 0731062) when used with goat anti-human IgG(H+L) as the secondary antibody. The EC50 is 92 ng/mL.
Neutralization Inhibiting STAT-5 Signaling
The stimulation of STAT5-Luciferase expression by the recombinant human TSLP (Cat.#: 0721061) in the HEK293 cells (Cat.#: 0611142) is neutralized by the Anti-TSLP antibody (Cat.#: 0731062) in a dose-dependent manner. The ND50 is typically 6.21 μg/mL.
Blocking TSLPR binding
In a sandwich ELISA, a concentration of 1μg/mL (100 μL/well) of anti-TSLP Ab (Cat.#: 0731062) will block binding of recombinant human TSLPR (1 μg/mL) (Cat. #: 0721112) to the recombinant human TSLP (Cat.#: 0721061) in a dose-dependent manner. The ND50 is 1.49 μg/mL.
Please note: Optimal concentrations should be determined by each application for each lab.
匯智泰康是一家位于中美兩地的生物醫(yī)藥合同研發(fā)機(jī)構(gòu)，整合中美兩地的藥物研發(fā)技術(shù)服務(wù)平臺，基于AAALAC、GLP、ISO/IEC 17025實(shí)驗室認(rèn)證，面向全球企業(yè)及研發(fā)機(jī)構(gòu)提供分析化學(xué)、DMPK、藥理藥效、生物學(xué)、以及毒理安全性評價產(chǎn)品與服務(wù)。
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關(guān)鍵字： TSLPAntybody;TSLP抗體;抗體;
匯智和源是一家專注于亞細(xì)胞酶，原代細(xì)胞，類器官等生物試劑解決方案的創(chuàng)新型企業(yè)，公司圍繞原代細(xì)胞相關(guān)產(chǎn)品，開發(fā)了肝溶酶體、肝微粒體/肝S9/誘導(dǎo)肝S9/肝Cytosol、CYP/UGT重組酶等亞細(xì)胞酶，原代肝細(xì)胞/腎細(xì)胞/肺細(xì)胞、原代PBMC，SMC等原代細(xì)胞及細(xì)胞分離、磁珠分選、細(xì)胞擴(kuò)增試劑盒、細(xì)胞培養(yǎng)基、凍存液產(chǎn)品，原代肝細(xì)胞三明治模型/3D成球、原代肝細(xì)胞類器官等類器官產(chǎn)品，為創(chuàng)新藥研發(fā)體外評價提供關(guān)鍵工具，實(shí)現(xiàn)原代細(xì)胞等高端生物試劑國產(chǎn)替代。公司累計服務(wù)客戶超2000家，包括藥明康德，康龍化成，昭衍，Sanofi，MERCK，BMS，百濟(jì)神州，恒瑞醫(yī)藥等知名CRO和創(chuàng)新藥企。